Developing clinical learning issues

• Pathology - the causes, course and complications of disease (ranked in order of probability and significance).  Understanding how they disrupt structure (anatomy) or function (physiology) and how these translate into symptoms and signs.
• Pharmacology - how drugs alter body physiology, major or common side effects, precautions when prescribing in certain conditions
• Therapeutics - a general schema of how to initiate a treatment regime for a disease and when to modify or withdrawal therapy including risk:benefit ratios
• Preventative care -  determining the risk:benefit ratio for primary, secondary and tertiary prevention in management of disease 
• Clinical skills - possessing a detailed and methodical repertoire of clinical questions (and follow-through questions), able to obtain a meticulous, accurate and unbiased account from a patient,  a systematic approach to clinical examination for each body system and interpreting the possible causes for abnormal findings.
• Clinical science - the typical and atypical clinical presentations of disease (including complications), methods of evaluating severity of a condition, being able to generate an appropriate differential list for a given set of abnormal symptoms, signs or investigative results. 
• Investigation - knowing in which patient samples they are best applied, understanding the possible interpretations of the test result,  understanding the overall accuracy of tests, appreciate situations that result in inaccuracy (sensitivity, specificity, predictive values)