REVERSAL OF ENOXAPARIN

TIME SINCE LAST ENOXAPARIN DOSE < 8 hrs 8-12 hrs > 12 hrs
PROTAMINE SULPHATE DOSE 1mg per mg enoxaparin 0.5 mg per mg enoxaparin Nil
  • Can be repeated at 0.5mg per mg enoxaparin
  • 60% maximal reversal achievable

Adapted from LMHS guidelines