Blood component therapy - Acquired conditions

See Assessing severity of Bleeding

Aims in unstable patient:

  • Hb > 7g/L
  • INR < 1.5
  • Fibrinogen level 1 > g/dL
  • Factor activity > 30%
  • Platelets > 50-100 x 109/L

 

Thrombocytopenia

Indications for treatment

Dose

5-10ml/kg platelets

Hypofibrinogenaemia

Indications for treatment

NB treat low fibrinogen in snake bite with antivenom (see Snakebite)

Dose

1ml/kg cryoprecipitate OR
10ml/kg FFP

Prolonged INR

see Over-anticoagulation