{"id":71,"date":"2016-07-23T12:51:08","date_gmt":"2016-07-23T12:51:08","guid":{"rendered":"http:\/\/emedsa.org.au\/CoreMed\/?p=71"},"modified":"2016-08-16T13:38:58","modified_gmt":"2016-08-16T13:38:58","slug":"immunocompromise","status":"publish","type":"post","link":"http:\/\/emedsa.org.au\/CoreMed\/2016\/07\/23\/immunocompromise\/","title":{"rendered":"Immunocompromise"},"content":{"rendered":"<p><a href=\"http:\/\/twitter.com\/share?url=http%3A%2F%2Femedsa.org.au%2FCoreMed%2F2016%2F07%2F23%2Fimmunocompromise%2F&amp;count=none&amp;text=Immunocompromise - CoreMed\" class=\"twitter-share-button\">Tweet<\/a><\/p><p><strong>Introduction<\/strong><\/p>\n<p>Despite the advent of antibiotics, Infection still remains a major cause of death either in isolation or as the terminal complication of underlying chronic illness.\u00a0 There are a number of overlooked factors that reduce a patient&#8217;s immunity and increase their susceptibility to serious infection and sepsis.\u00a0 <em>These should be reviewed in any patient with suspected infection.<\/em><\/p>\n<p><strong>High risk groups<\/strong> &#8211; Chemotherapy patients, Organ Transplant patients, Neonates, AIDS<\/p>\n<p><em>High risk patients may not manifest classical features of infection i.e. fever, elevated WCC\/CRP and a high degree of suspicion for sepsis should be entertained (and aggressive investigation and early treatment)\u00a0if there are focal signs of infection<\/em><\/p>\n<p><strong>\u00a0Anatomical considerations<\/strong><\/p>\n<ul>\n<li><strong>Presence of any foreign body in the human body<\/strong> e.g catheters, cannula, tubes, stents, prosthesis, implants<\/li>\n<li><strong>Impaired anatomical barriers<\/strong> e.g. inflamed or traumatised skin, inability to cough, urinary incontinence<\/li>\n<\/ul>\n<p><strong>Immunological considerations<\/strong><\/p>\n<ul>\n<li><strong>Acquired<\/strong>\u00a0 &#8211; usually from <a href=\"http:\/\/emedsa.org.au\/CoreMed\/2016\/07\/23\/immunosuppression\/\">Immnomodulators or Immunosupressants<\/a>, HIV<\/li>\n<li><strong>Congenital<\/strong> (rare but more often seen in paediatric population)<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>TweetIntroduction Despite the advent of antibiotics, Infection still remains a major cause of death either in isolation or as the terminal complication of underlying chronic illness.\u00a0 There are a number&#8230; <a href=\"http:\/\/emedsa.org.au\/CoreMed\/2016\/07\/23\/immunocompromise\/\">Read more &raquo;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"episode_type":"","audio_file":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","date_recorded":"","explicit":"","block":"","filesize_raw":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-71","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"http:\/\/emedsa.org.au\/CoreMed\/wp-json\/wp\/v2\/posts\/71","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/emedsa.org.au\/CoreMed\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/emedsa.org.au\/CoreMed\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/emedsa.org.au\/CoreMed\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/emedsa.org.au\/CoreMed\/wp-json\/wp\/v2\/comments?post=71"}],"version-history":[{"count":4,"href":"http:\/\/emedsa.org.au\/CoreMed\/wp-json\/wp\/v2\/posts\/71\/revisions"}],"predecessor-version":[{"id":612,"href":"http:\/\/emedsa.org.au\/CoreMed\/wp-json\/wp\/v2\/posts\/71\/revisions\/612"}],"wp:attachment":[{"href":"http:\/\/emedsa.org.au\/CoreMed\/wp-json\/wp\/v2\/media?parent=71"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/emedsa.org.au\/CoreMed\/wp-json\/wp\/v2\/categories?post=71"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/emedsa.org.au\/CoreMed\/wp-json\/wp\/v2\/tags?post=71"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}